医学

过敏学

解剖学和形态学

男科学

麻醉学

听力与言语-语言病理学

行为科学

心脏和心血管系统

细胞和组织工程学

临床神经病学

危重症监护医学

牙科，口腔外科和医学

皮肤病学

急诊医学

内分泌学和新陈代谢

肠胃学和肝脏学

老人病学和老年医学

卫生保健科学和服务

血液学

免疫学

传染病

综合和补充性医学

医学伦理学

医学信息学

医学实验室技术

医学，全科和内科

医学，法律

医学，研究和试验

神经影像学

神经系统科学

护理

营养学和饮食学

产科医学和妇科医学

肿瘤学

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整形外科学

耳鼻喉科学

病理学

儿科学

周围血管疾病

药理学和药剂学

生理学

基本医疗保健

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公共、环境和职业卫生

放射学，核医学和医学成像

康复学

生殖生物学

呼吸系统

风湿病学

运动科学

外科学

毒理学

热带医学

泌尿学和肾脏学

兽医学

病毒学

伦理学

老年医学

健康政策和服务

心理学，临床

心理学，精神分析

你正在浏览ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS期刊下所有文献
  • Structure-function correlation of human programmed cell death 5 protein.

    abstract：:Human programmed cell death 5 (PDCD5) is a translocatory protein playing an important role in the apoptotic process of cells. Although there are accumulated data about PDCD5 function, the correlation of the structure with the function of PDCD5 has not been investigated. Here, we report the studies of structure-functio...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2009.03.018

    authors： Yao H,Xu L,Feng Y,Liu D,Chen Y,Wang J

    更新日期：2009-06-15 00:00:00

  • A novel NADP(+)-dependent dehydrogenase activity for 7alpha/beta- and 11beta-hydroxysteroids in human liver nuclei: A third 11beta-hydroxysteroid dehydrogenase.

    abstract：:Human tissue from uninvolved liver of cancer patients was fractionated using differential centrifugation and characterized for 11betaHSD enzyme activity against corticosterone, dehydrocorticosterone, 7alpha- and 7beta-hydroxy-dehydroepiandrosterone, and 7-oxo-dehydroepiandrosterone. An enzyme activity was observed in ...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2009.04.010

    authors： Robinzon B,Prough RA

    更新日期：2009-06-15 00:00:00

  • Thermal stability and redox properties of M. tuberculosis CuSOD.

    abstract：:The superoxide dismutase from Mycobacterium tuberculosis is the only Cu-containing superoxide dismutase that lacks zinc in the active site. To explore the structural properties of this unusual enzyme, we have investigated its stability by differential scanning calorimetry. We have found that the holo-enzyme is signifi...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2009.04.005

    authors： D'Orazio M,Cervoni L,Giartosio A,Rotilio G,Battistoni A

    更新日期：2009-06-15 00:00:00

  • Inhibition of uncoupling protein 2 by genipin reduces insulin-stimulated glucose uptake in 3T3-L1 adipocytes.

    abstract：:Uncoupling protein 2 (UCP2) was reported to be involved in insulin-glucose homeostasis, based on well established event that inhibition of UCP2 stimulates insulin secretion in pancreatic beta-cells. However, the role of UCP2 on insulin-stimulated glucose uptake in adipose tissue, which is an indispensable process in i...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2009.02.017

    authors： Zhou H,Zhao J,Zhang X

    更新日期：2009-06-01 00:00:00

  • Binding of peroxiredoxin 6 to substrate determines differential phospholipid hydroperoxide peroxidase and phospholipase A(2) activities.

    abstract：:Peroxiredoxin 6 (Prdx6) differs from other mammalian peroxiredoxins both in its ability to reduce phospholipid hydroperoxides at neutral pH and in having phospholipase A(2) (PLA(2)) activity that is maximal at acidic pH. We previously showed an active site C47 for peroxidase activity and a catalytic triad S32-H26-D140...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2009.02.008

    authors： Manevich Y,Shuvaeva T,Dodia C,Kazi A,Feinstein SI,Fisher AB

    更新日期：2009-05-15 00:00:00

  • Characterization of the ATPase activity of a novel chimeric fusion protein consisting of the two nucleotide binding domains of MRP1.

    abstract：:Nucleotide Binding Domains (NBDs) are responsible for the ATPase activity of the multidrug resistance protein 1 (MRP1). A series of NBD1-linker-NBD2 chimeric fusion proteins were constructed, expressed and purified, and their ATPase activities were analyzed. We report here that a GST linked NBD1(642-890)-GST-NBD2(1286...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2009.03.003

    authors： Wan L,Liang X,Huang Y

    更新日期：2009-05-15 00:00:00

  • Binding and stabilization of transthyretin by curcumin.

    abstract：:Biophysical evidences suggest that transthyretin (TTR) tetramer dissociation to the monomeric intermediate and subsequent polymerization leads to amyloid fibril formation, which is implicated in the pathogenesis of familial amyloid polyneuropathy (FAP) and senile systemic amyloidosis (SSA). Hence, inhibition of fibril...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2009.02.013

    authors： Pullakhandam R,Srinivas PN,Nair MK,Reddy GB

    更新日期：2009-05-15 00:00:00

  • Peroxynitrite signaling in human erythrocytes: synergistic role of hemoglobin oxidation and band 3 tyrosine phosphorylation.

    abstract：:Peroxynitrite crosses the red blood cell (RBC) membrane and reacts with hemoglobin (Hb) producing mainly metHb, which is reduced back to ferrousHb by NADH- and NADPH-dependent reductases. Peroxynitrite also induces band 3 (B3) tyrosine phosphorylation, a signaling pathway believed to activate glucose metabolism. This ...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章,评审

    doi：10.1016/j.abb.2008.10.025

    authors： Metere A,Iorio E,Pietraforte D,Podo F,Minetti M

    更新日期：2009-04-15 00:00:00

  • Development, evaluation and application of tripeptidyl-peptidase II sequence signatures.

    abstract：:Tripeptidyl-peptidase II (TPP II) is a cytosolic peptidase that has been implicated in fat formation and cancer, apparently independent of the enzymatic activity. In search for alternative functional regions, conserved motifs were identified and eleven signatures were constructed. Seven of the signatures covered previ...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2009.01.007

    authors： Eriksson S,Gutiérrez OA,Bjerling P,Tomkinson B

    更新日期：2009-04-01 00:00:00

  • A conserved hydrophobic core at Bcl-xL mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein.

    abstract：:Bcl-2 family proteins regulate apoptosis through their homo- and heterodimerization. By protein sequence analysis and structural comparison, we have identified a conserved hydrophobic core at the BH1 and BH2 domains of Bcl-2 family proteins. The hydrophobic core is stabilized by hydrophobic interactions among the resi...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2009.01.003

    authors： Feng Y,Zhang L,Hu T,Shen X,Ding J,Chen K,Jiang H,Liu D

    更新日期：2009-04-01 00:00:00

  • Carotenoid breakdown products the-norisoprenoids-in wine aroma.

    abstract：:In recent years there has been much interest in the role that products of carotenoid breakdown--the norisoprenoids--may play in wine aroma. The basis for this interest is that norisoprenoids have very low olfactory perception thresholds and so have a high sensorial impact on wine aroma. The norisoprenoids can be forme...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章,评审

    doi：10.1016/j.abb.2009.01.008

    authors： Mendes-Pinto MM

    更新日期：2009-03-15 00:00:00

  • Lipid-induced conformation of helix 7 from the pore-forming domain of the Bacillus thuringiensis Cry4Ba toxin: implications for toxicity mechanism.

    abstract：:Helix 7 in the Cry4Ba-pore-forming domain contains conserved Tyr(249) and Phe(264) that are crucially involved in mosquito-larvicidal activity. We have now characterized lipid-induced conformation of a 27-residue Cry4Ba-alpha7 peptide in phospholipid membranes using ATR-FTIR and hydrogen/deuterium (H(+)/D(+)) exchange...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.11.025

    authors： Tiewsiri K,Fischer WB,Angsuthanasombat C

    更新日期：2009-02-01 00:00:00

  • Antiproliferative activity and apoptosis-inducing mechanism of Concanavalin A on human melanoma A375 cells.

    abstract：:The objective of this study was to investigate the antiproliferative activity and apoptosis-inducing mechanism of Concanavalin A (ConA) on human melanoma A375 cells. We firstly simulated the three-dimensional structure of ConA. Subsequently, we found that ConA possessed remarkable antiproliferative effect on A375 cell...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.12.003

    authors： Liu B,Li CY,Bian HJ,Min MW,Chen LF,Bao JK

    更新日期：2009-02-01 00:00:00

  • Ethanol exposure decreases mitochondrial outer membrane permeability in cultured rat hepatocytes.

    abstract：:Mitochondrial metabolism depends on movement of hydrophilic metabolites through the mitochondrial outer membrane via the voltage-dependent anion channel (VDAC). Here we assessed VDAC permeability of intracellular mitochondria in cultured hepatocytes after plasma membrane permeabilization with 8 microM digitonin. Block...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.10.036

    authors： Holmuhamedov E,Lemasters JJ

    更新日期：2009-01-15 00:00:00

  • p53 regulates Hsp90beta during arsenite-induced cytotoxicity in glutathione-deficient cells.

    abstract：:p53, a tumor suppressor and transcription factor, is a critical modulator in the cellular response to stress. Exposure of glutathione-deficient GCS-2 cells to arsenite significantly phosphorylated and stabilized p53. In addition, p53 transcriptionally repressed Hsp90beta gene expression. Mutation analysis revealed a p...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.10.024

    authors： Habib GM

    更新日期：2009-01-01 00:00:00

  • Losartan, an antagonist of AT1 receptor for angiotensin II, attenuates lipopolysaccharide-induced acute lung injury in rat.

    abstract：:Angiotensin II (Ang II) plays an important role in inflammatory process. Acute lung injury (ALI), an inflammatory disorder of the lung, is commonly associated with endotoxemia; however, the mechanism that endotoxin (lipopolysaccharide, LPS) induces the inflammatory response in ALI is not well defined. Here, we showed,...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.09.019

    authors： Liu L,Qiu HB,Yang Y,Wang L,Ding HM,Li HP

    更新日期：2009-01-01 00:00:00

  • Effect of the phosphate substrate on drug-inhibitor binding to human purine nucleoside phosphorylase.

    abstract：:The thermodynamics of the drug-inhibitors acyclovir, ganciclovir, and 9-benzylguanine binding to human purine nucleoside phosphorylase (hsPNP) were determined from isothermal titration calorimetry as a function of the substrate phosphate ion (Pi) concentration from 0 to 0.125 M and temperature from 15 degrees C to 35 ...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.10.008

    authors： Todorova NA,Schwarz FP

    更新日期：2008-12-15 00:00:00

  • Resveratrol protects against oxidative injury induced by H2O2 in acute hippocampal slice preparations from Wistar rats.

    abstract：:There is a current interest in dietary compounds (such as trans-resveratrol) that can inhibit or reverse oxidative stress, the common pathway for a variety of brain disorders, including Alzheimer's disease and stroke. The objective of the present study was to investigate the effects of resveratrol, under conditions of...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.09.006

    authors： de Almeida LM,Leite MC,Thomazi AP,Battu C,Nardin P,Tortorelli LS,Zanotto C,Posser T,Wofchuk ST,Leal RB,Gonçalves CA,Gottfried C

    更新日期：2008-12-01 00:00:00

  • Comparative effects of cationic triarylmethane, phenoxazine and phenothiazine dyes on horse serum butyrylcholinesterase.

    abstract：:The kinetic effects of a selection of triarylmethane, phenoxazine and phenothiazine dyes (pararosaniline (PR), malachite green (MG), methyl green (MeG); meldola blue (MB), nile blue (NB), nile red (NR); methylene blue (MethB)) and of ethopropazine on horse serum butyrylcholinesterase were studied spectrophotometricall...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.07.006

    authors： Yücel YY,Tacal O,Ozer I

    更新日期：2008-10-15 00:00:00

  • Difference in polymerization and steady-state dynamics of free and gelsolin-capped filaments formed by alpha- and beta-isoactins.

    abstract：:The polymerization of scallop beta-like actin is significantly slower than that of skeletal muscle alpha-actin. To reveal which steps of polymerization contribute to this difference, we estimated the efficiency of nucleation of the two actins, the rates of filament elongation at spontaneous and gelsolin-nucleated poly...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.06.016

    authors： Khaitlina S,Hinssen H

    更新日期：2008-09-15 00:00:00

  • Mechanistic analysis of Mycobacterium tuberculosis Rv1347c, a lysine Nepsilon-acyltransferase involved in mycobactin biosynthesis.

    abstract：:Mycobactin acylation plays a crucial role in the ability of Mycobacterium tuberculosis to acquire intracellular iron during infection. M. tuberculosis Rv1347c, the lysine N(epsilon)-acyltransferase responsible for mycobactin acylation, represents a valid target for the development of novel anti-tubercular agents. Here...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.05.013

    authors： Frankel BA,Blanchard JS

    更新日期：2008-09-15 00:00:00

  • Role of the conserved distal heme asparagine of coral allene oxide synthase (Asn137) and human catalase (Asn148): mutations affect the rate but not the essential chemistry of the enzymatic transformations.

    abstract：:A catalase-related allene oxide synthase (cAOS) and true catalases that metabolize hydrogen peroxide have similar structure around the heme. One of the distal heme residues considered to help control catalysis is a highly conserved asparagine. Here we addressed the role of this residue in metabolism of the natural sub...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.07.011

    authors： Gao B,Boeglin WE,Brash AR

    更新日期：2008-09-15 00:00:00

  • The impact of the 67kDa laminin receptor on both cell-surface binding and anti-allergic action of tea catechins.

    abstract：:Here, we investigated the structure-activity relationship of major green tea catechins and their corresponding epimers on cell-surface binding and inhibitory effect on histamine release. Galloylated catechins; (-)-epigallocatechin-3-O-gallate (EGCG), (-)-gallocatechin-3-O-gallate (GCG), (-)-epicatechin-3-O-gallate (EC...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.03.002

    authors： Fujimura Y,Umeda D,Yamada K,Tachibana H

    更新日期：2008-08-15 00:00:00

  • Insight into the apoptosis-inducing action of alpha-bisabolol towards malignant tumor cells: involvement of lipid rafts and Bid.

    abstract：:In a precedent report we showed that alpha-bisabolol, a sesquiterpene present widely in the plant kingdom, exerts a rapid and efficient apoptosis-inducing action selectively towards human and murine malignant glioblastoma cell lines through mitochondrial damage. The present study extends these data demonstrating the a...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.02.004

    authors： Darra E,Abdel-Azeim S,Manara A,Shoji K,Maréchal JD,Mariotto S,Cavalieri E,Perbellini L,Pizza C,Perahia D,Crimi M,Suzuki H

    更新日期：2008-08-15 00:00:00

  • The application of proteomics for studying the neurorescue activity of the polyphenol (-)-epigallocatechin-3-gallate.

    abstract：:Accumulating evidence suggests that oxidative stress resulting in reactive oxygen species generation plays a pivotal role in neurodegenerative diseases, supporting the realization of the use of radical scavengers, metal chelator agents, such as the natural polyphenols for therapy. In this study, we have focused on spe...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.01.004

    authors： Weinreb O,Amit T,Youdim MB

    更新日期：2008-08-15 00:00:00

  • Effect of dihydrocaffeic acid on UV irradiation of human keratinocyte HaCaT cells.

    abstract：:Dihydrocaffeic acid, a dietary constituent and a microbial metabolite of flavonoids, is an antioxidant, but few biological effects have been examined. After its production by microflora in the colon, dihydrocaffeic acid is absorbed and found in plasma as a combination of free and metabolized forms. Excess solar UV rad...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.01.019

    authors： Poquet L,Clifford MN,Williamson G

    更新日期：2008-08-15 00:00:00

  • The plasma membrane Ca2+ ATPase of animal cells: structure, function and regulation.

    abstract：:Most important processes in cell life are regulated by calcium (Ca2+). A number of mechanisms have thus been developed to maintain the concentration of free Ca2+ inside cells at the level (100-200nM) necessary for the optimal operation of the targets of its regulatory function. The systems that move Ca2+ back and fort...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章,评审

    doi：10.1016/j.abb.2008.02.026

    authors： Di Leva F,Domi T,Fedrizzi L,Lim D,Carafoli E

    更新日期：2008-08-01 00:00:00

  • Mechanistic studies of sodium pump.

    abstract：:Sodium pump was the first ion pump discovered. A member of the family of active transporters that catalyze adenosine 5'-triphosphate hydrolysis by forming a phosphorylated enzyme intermediate, sodium pump couples the energy released to unequal countertransport of sodium and potassium ions. The ion gradient generated b...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章,评审

    doi：10.1016/j.abb.2008.05.017

    authors： Faller LD

    更新日期：2008-08-01 00:00:00

  • Chaperonins: The hunt for the Group II mechanism.

    abstract：:Chaperonins are multi-subunit complexes that enhance the efficiency of protein-folding reactions by capturing protein substrates in their central cavities. They occur in all prokaryotic and eukaryotic cell types and, alone amongst molecular chaperones, chaperonin knockouts are always lethal. Chaperonins come in two fo...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章,评审

    doi：10.1016/j.abb.2008.03.015

    authors： Bigotti MG,Clarke AR

    更新日期：2008-06-15 00:00:00

  • Iron-sulfur cluster biosynthesis in bacteria: Mechanisms of cluster assembly and transfer.

    abstract：:Iron-sulfur [Fe-S] clusters are ubiquitous ancient prosthetic groups that are required to sustain fundamental life processes. Formation of intracellular [Fe-S] clusters does not occur spontaneously but requires a complex biosynthetic machinery. Different types of [Fe-S] cluster assembly systems have been discovered. A...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章,评审

    doi：10.1016/j.abb.2007.12.014

    authors： Fontecave M,Ollagnier-de-Choudens S

    更新日期：2008-06-15 00:00:00

  • Biosynthesis of vitamin B2: Structure and mechanism of riboflavin synthase.

    abstract：:The biosynthesis of one riboflavin molecule requires one molecule of GTP and two molecules of ribulose 5-phosphate as substrates. GTP is hydrolytically opened, converted into 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione by a sequence of deamination, side chain reduction and dephosphorylation. Condensation with 3,...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章,评审

    doi：10.1016/j.abb.2008.02.008

    authors： Fischer M,Bacher A

    更新日期：2008-06-15 00:00:00

  • Communications between bone cells and hematopoietic stem cells.

    abstract：:The skeletal system, while characterized by a hard tissue component, is in fact an extraordinarily dynamic system, with disparate functions ranging from structural support, movement and locomotion and soft-organ protection, to the maintenance of calcium homeostasis. Amongst these functions, it has long been known that...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章,评审

    doi：10.1016/j.abb.2008.04.001

    authors： Porter RL,Calvi LM

    更新日期：2008-05-15 00:00:00

  • Transmembrane domain interactions affect the stability of the extracellular domain of the human NTPDase 2.

    abstract：:Human NTPDase2 and chicken NTPDase8 are cell surface nucleotidases that contain two transmembrane domains (TMD) and five apyrase conserved regions (ACRs). ACR1 is located near the N-terminal TMD whereas ACR5 is located near the C-terminal TMD. The human NTPDase2 activity is decreased by low concentration of NP-40 and ...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.02.011

    authors： Chiang WC,Knowles AF

    更新日期：2008-04-15 00:00:00

  • The regulatory function of N-terminal AAA+ ATPase domain of eukaryote-like archaeal Orc1/Cdc6 protein during DNA replication initiation.

    abstract：:Archaeal replication machinery represents a core version of this in eukaryotes. The crenarchaeon Sulfolobus solfataricus has the potential to be a powerful model system to understand the central mechanism of eukaryotic DNA replication because it contains three active origins of replication and three eukaryote-like Orc...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.01.007

    authors： He ZG,Feng Y,Wang J,Jiang PX

    更新日期：2008-03-15 00:00:00

  • Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450.

    abstract：:Epoxidation and hydroxylation of arachidonic acid (AA) are both catalyzed by cytochromes P450s (CYPs). The oxidized metabolites are known to be involved in the regulation of vascular tone and renal function. By using a panel of 15 human recombinant CYPs, this study demonstrates that other polyunsaturated long-chain fa...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2008.01.002

    authors： Fer M,Dréano Y,Lucas D,Corcos L,Salaün JP,Berthou F,Amet Y

    更新日期：2008-03-15 00:00:00

  • Up-regulation of hyaluronan synthase genes in cultured human epidermal keratinocytes by UVB irradiation.

    abstract：:Hyaluronan controls keratinocyte proliferation and regeneration. We examined effect of UV on the expression of hyaluronan synthases (HASs) and hyaluronidases in cultured normal human newborn foreskin epidermal keratinocytes, NHEK(F). HAS3 mRNA was expressed predominantly and HAS2 mRNA expressed in lesser amounts and b...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2007.12.004

    authors： Kakizaki I,Itano N,Kimata K,Hanada K,Kon A,Yamaguchi M,Takahashi T,Takagaki K

    更新日期：2008-03-01 00:00:00

  • Association of transient receptor potential canonical type 3 (TRPC3) channel transcripts with proinflammatory cytokines.

    abstract：:We investigated whether expression of non-selective cation channels of the transient receptor potential canonical (TRPC) channel family are associated with proinflammatory cytokines in monocytes. Using quantitative RT-PCR we studied the expression of TRPC3, interleukin-1beta (IL-1beta), and tumor necrosis factor-alpha...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2007.12.006

    authors： Thilo F,Scholze A,Liu DY,Zidek W,Tepel M

    更新日期：2008-03-01 00:00:00

  • Molecular and biochemical characterization of benzalacetone synthase and chalcone synthase genes and their proteins from raspberry (Rubus idaeus L.).

    abstract：:Two new members of the polyketide synthase (PKS) gene family (RiPKS4 and RiPKS5) were cloned from raspberry fruits (Rubus idaeus L., cv Royalty) and expressed in Escherichia coli. Characterization of the recombinant enzyme products indicated that RiPKS4 is a bifunctional polyketide synthase producing both 4-hydroxyben...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2007.11.013

    authors： Zheng D,Hrazdina G

    更新日期：2008-02-15 00:00:00

  • Diabetes alters LDL receptor and PCSK9 expression in rat liver.

    abstract：:Since the hepatic LDL receptor is regarded as a major determinant of plasma LDL levels, the effect of diabetes on the expression of this receptor was examined in rat liver. Inducing diabetes with streptozotocin caused a significant reduction in hepatic LDL receptor mRNA levels in concert with an increase in serum chol...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2007.11.009

    authors： Niesen M,Bedi M,Lopez D

    更新日期：2008-02-15 00:00:00

  • Antagonistic and agonistic effects of indigoids on the transformation of an aryl hydrocarbon receptor.

    abstract：:Halogenated and polycyclic aromatic hydrocarbons, exogenous ligands of the aryl hydrocarbon receptor (AhR), cause various toxicological effects through the transformation of the AhR. In this study, we investigated the antagonistic effects of indigoids on the transformation in addition to their agonistic ones. In a cel...

    journal_title：Archives of biochemistry and biophysics

    pub_type： 杂志文章

    doi：10.1016/j.abb.2007.11.021

    authors： Nishiumi S,Yamamoto N,Kodoi R,Fukuda I,Yoshida K,Ashida H

    更新日期：2008-02-15 00:00:00

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